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Efek Antibakteri in Vitro dan Antidiare in Vivo Infusa Akar Sago (Metroxylon Sagu) (Antibacterial Invitro and Antidiarrhea Invivo Effects of the Infusion of Sago Roots (Metroxylon Sagu)
Fresh root of sago (Mettroxylon sagu) traditionally has been usedas an antidiarrhea in South South Kalimantan community. However, there is no Scientific data yet to support it. The aims of this study were to investigate the antibacterial effect of the infusion of sago root on Salmonella typhi (S. Thyphi) as one of bacteria causing diarrhea in vitro and to find out its effects as antidiarrhea in male mice induced by castoe oil in vivo. This experimental study measured the inhibitory zone in S. Typhi culture and to ount the frequency and duration of diarrhea. It used 3 concentrations, i.e. 10%; 20% and 40% of the infusion of sago root. Chloramphenicol and aquadest were used as positive and negative control groups respectively in in vitro study, whereas in in viv on loperamide was positive control group. Chloramphenicol was used since it is an antibiotic standard for eradicating S. Thypi, whereas Loperaminde is antiperistic agent from declining the frequency and duration of diarrhea. The infusion inhibited radicalzone of S. Typhi culture by 7.8; 9.8; and 10 mm, decreased the frequency of diarrhea 24.235; 40.54% and 16.22% and decreased the duration of diarrhea 26.69%; 52.92% and 10.27% at concentration 10%, 20% and 40%, respectively/ As conclusion the infusion of sago root has the potency as anti bacteria and decrease in frequency and duration of diarrhea. The best concentration of the ufusion of sago root is 20%
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