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Hubungan antara Hiperglikemia dan Mortalitas pada Anak dengan Sepsis di Ruang Rawat Inap Intensif RSUD Dr. Moewardi Surakarta

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Sepsis is a major cause of infant and child mortality. Hyperglycemia worsens situation in patients with sepsis and increases mortality. Unfortunately, hyperglycemia in patients with sepsis is of ten ignored by clinicians. This study aimed to estimate the association between hyperglycemia and mortality in children with sepsis after controlling for multi-organ dysfunctions (MOD), age, and nutritional status.A prospective cohort study was conducted at the Pediatric Intensive Care Unit (PICU),
RSUD Dr. Moewardi Surakarta on 85 child patients aged 1 month to 18 years who were diagnosed as sepsis. Hyperglycemia was determined using blood glocose of 200mg/ dl cut-off point. Multivariate Cox regression analysis was performed to analyze the association between mortality and hyperglycemia,while controlling for confounding variables including MOD, age, and nutritional status. The strength of association was measured in hazard ratio (HR) with its 95% confidence interval.Cox regression analysis showed a statistically significant moderate association between
hyperglycemia and mortality (HR= 2.78; 95% CI 1,34 to 5.77; p=0.006). MOD was strongly related with mortality (HR= 5.25; 95% CI 2,20 to 12.49; p

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Detail Information

Series Title

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Call Number

Jurnal Kedokteran Indonesai, 2(1) 2011:34-38

Publisher

Surakarta : Fk. Universitas Sebelas Maret., 2011

Collation

4p.

Language

ISBN/ISSN

2086-5171

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

mortality
inpatient
SEPSIS
Hyperglycemia

Specific Detail Info

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