Hubungan Pemberian Zink dengan Hitung Limfosit dan Lama Rawat Inap pada Anak dengan Infeksi Virus Dengue di RSUD Dr. Moewardi Surakarta | Perpustakaan dan Galeri Kebijakan Kesehatan

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Hubungan Pemberian Zink dengan Hitung Limfosit dan Lama Rawat Inap pada Anak dengan Infeksi Virus Dengue di RSUD Dr. Moewardi Surakarta

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In theory, lymphocyte count increases in pediatric patients with dengue virus infection,because this infection increases apoptosis process and activation of T lymphocyte function, Th1 cytokine production, and B lymphocytes. Administration of zinc is hypothsized to affect immunity changes as shown by these biomarkers. This study aimed to examine the effect of zinc on lymphocyte count and length of stay in pediatric patients with dengue virus infection.This study was a randomized controlled trial. A sample of 78 pediatric inpatients with dengue virus infection was selected for study at Dr. Moewardi Hospital Surakarta, between October
2010 and March 2011. This sample was divided into 2 groups, consisting of 39 children receiving standard therapy plus zinc and 39 children eceiving standard therapy alone. The dependent variables under study were lymphocyte count and length of stay (days) The independent variable was
administration of zinc. The mean difference in lymphocyte count and length of stay between the two groups was tested by independent t, using SPSS version 17.0.No statistically significant difference in means was shown of lympocyte count between the two groups (p=0.313), meaning that there is no association between administration of zinc and lymphocyte count. In contrast, there was statistically significant difference in means of length of stay(days) between the two groups (p=0.006). Patients receiving zinc had 0.62 days shorter length of stay than those without zinc. Administration of zinc is associated with shortening of length of stay but not associated with lymphocyte count.

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Belum memasukkan lokasi Jurnal Kedokteran Indonesai;2(1):30-33

A00011812

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Judul Seri: -
No. Panggil: Jurnal Kedokteran Indonesai,2(1):30-33
Penerbit: Surakarta : Fk. Universitas Sebelas Maret., 2011
Deskripsi Fisik: -
Bahasa
ISBN/ISSN: 2086-5171
Klasifikasi: -
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: -
Subjek: lymphocytes
inpatient
zinc
DENGUE VIRUS
Info Detail Spesifik: -
Pernyataan Tanggungjawab: -

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