Text

Pengaruh Pemberian Akar Pasak Bumi (Eurycoma longifolia Jack) pada Fungsi Hepar (The Effect of the Extract of Pasak Bumi Roots (Eurycoma longifolia Jack) on Liver Function)

---

The aim of this research is to study the effects of the methanol extract and its delived facrtion (n-hexane, chlotoform, ethyl acetate, and methanol-water) on liver function of male rats. The treatment groups were administered 500 mg/kg body weight of metanol extract and its derived fractions (n-hexane,chloroform, ethyl acetate, n-butanol, methanol-water) of E. Longifolia for 7consecutive days. Positive control group received 25 mg silymarin.kg body weight and negative control group received 2 ml aquadest/kg body weight daily for 7 consecutive days. Liver function was monitored by measuring alanine transaminase (ALT), aspartate transaminase (AST), total protein, alkaline phosphatase (ALP), total bilirubin, direct bilirubin, and indiarect bilirubin concentrations in the serum. Compared with control, oral administration ofmethanol extract and derived fractions of methanol extract of E. Longifolia root had no significant effects on liver function (p>0.05). Methanol-water fraction gave similar results to silymarin.

---

Availability

Detail Information

Series Title

-

Call Number

Majalah Farmasi Indonesia,22(1)2011:15-20

Publisher

Yogyakarta : Fakultas Farmasi UGM,., 2011

Collation

5p.

Language

ISBN/ISSN

0126-1037

Classification

-

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

plant extracts
liver
EURYCOMA

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment