Text

Pengaruh Pemberian Akar Pasak Bumi (Eurycoma longifolia Jack) pada Fungsi Hepar (The Effect of the Extract of Pasak Bumi Roots (Eurycoma longifolia Jack) on Liver Function)

---

The aim of this research is to study the effects of the methanol extract and its delived facrtion (n-hexane, chlotoform, ethyl acetate, and methanol-water) on liver function of male rats. The treatment groups were administered 500 mg/kg body weight of metanol extract and its derived fractions (n-hexane,chloroform, ethyl acetate, n-butanol, methanol-water) of E. Longifolia for 7consecutive days. Positive control group received 25 mg silymarin.kg body weight and negative control group received 2 ml aquadest/kg body weight daily for 7 consecutive days. Liver function was monitored by measuring alanine transaminase (ALT), aspartate transaminase (AST), total protein, alkaline phosphatase (ALP), total bilirubin, direct bilirubin, and indiarect bilirubin concentrations in the serum. Compared with control, oral administration ofmethanol extract and derived fractions of methanol extract of E. Longifolia root had no significant effects on liver function (p>0.05). Methanol-water fraction gave similar results to silymarin.

---

Ketersediaan

Informasi Detail

Judul Seri

-

No. Panggil

Majalah Farmasi Indonesia,22(1)2011:15-20

Penerbit

Yogyakarta : Fakultas Farmasi UGM,., 2011

Deskripsi Fisik

5p.

Bahasa

ISBN/ISSN

0126-1037

Klasifikasi

-

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

-

Subjek

plant extracts
liver
EURYCOMA

Info Detail Spesifik

-

Pernyataan Tanggungjawab

-

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar