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Suplementasi Seng dan Probiotik pada Diare Akut Cair Anak
Clinical trials have demostrated that zinc suplement during diarrhea Study that evaluated diet entriched with zinc and probiotic showed significant reduction on the duration of diarrhea. Whether this combination s beter than either supllement of zinc or probiotic alone is unknown. The objective of the study was to compare the duration of diarrhea among children with acute watery diarrhea given zinc probiotic and combined zinc-probiotic supllementation. Consecutive sampling from 6-24 months old hospitalized children with acute watery diarrhea in Kariadi hospital was done. There were 77 subjects randomized into 4 study groups. There groups were supplemented daily with zinc, probiotic, or zinc and probiotic and one group as control. Each group had standard therpay including rehydration and dietic. Data were analyzed with Chi-square test, t test and one way ANOVA. There were no differences in age, breastfeeding history, nutritional and socail economic status, day before adminission and level of zinc serum among groups. Suplemented group showed significant reduction on the durattion of diarrchea compared with control (p=0.02). There was no significant difference in the duration of diarrhea between zinc probiotic and zinc or probiotic groups (p=0.15). Zinc probiotic supplemented group had the lowest duration of diarrhea among groups. Zinc and probiotic are able to reduce the duration of acute watery diarrhea
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