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Sklerosis Sistemik Difus

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Abstract. Systemic sclerosis (scleroderma) is a connective tissue disease of the unknown causes that characterized by fibrosis of skin and visceral organs as well as micro vascular abnormalities. The prevalency of the patients is relatively low with 50-300 cases per 1 million of the population and the incidence of 2.3 to 22.8 cases per I million population per year; however, the risk on women is higher than men with a ratio of 3-4: 1. The diagnose of this disease is based on clinical examinations and other supporting tests. The management of the patients is done just to reduce or eliminate the complaints and to improve organ functions but unfortunately can not cure the disease. The figure for average life expectancy in patients with diffuse systemic sclerosis is about 70% in 5 years and 55% in 10 years. There was a case of systemic diffuse sclerosis disease on 34 year old woman. The diagnosis was based on the ARA criteria (thickening, tightening and hardening of skin around extremities, face, neck, and trunk or back and the loss of fingers substances), antj-SCL~70, manus rontgen, thigh skin biopsies, gastroduodenoscopy and echocardiography. The doctor did a series of treatment on the patient such as vasodilators, immunosuppressive, anti fibrotic, and proton pump inhibitors. (JKS 2010;2:93-98)

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Series Title

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Call Number

JKS Jurnal Kedokter Syiah Kuala;10(2))2010:93-97

Publisher

Banda Aceh : FK Universitas Syiah Kuala Darussalam Banda Aceh., 2010

Collation

4p.

Language

ISBN/ISSN

1412-1026

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

SCLERODERMA, SYSTEMIC

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