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Efek Pemberian Ekstrak Eurycoma Longifolia dan Pimpinella Alpina pada Spermatogenesis Tikus Spraque Dawly

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The effect of eurycoma longifolia and pimpinella alpina on spermatogenesis in male Spraoue Dawly
Background: Alternative medicine used to overcome infertility among others is using traditional herbs. Crops which often used are pasak bumi (Eurycoma longifolia) and purwaceng (Pimpinella alpina). Several studies reported that pasak bumi and purwaceng could improve testosterone, luteinizing hormone and follicle stimulating hormone level in animal. The aim of the study was to analyze whether the extract of Eurycoma longifolia and Pimpinefla a/pina had effect on motility and spermatogenesis in white male Spraque Dawly mouse.
Material and Method: Thirty white male mice, aged 40 days, with mean body weight of 200 grams were divided into 10 groups randomly. Each mal/se was placed into individual cage and was given 25 mg Pimpinella alpina, 25 mg Eurycoma longifolia Jack and plain water in control group. Food was given ad libitum. All the treatment was given every morning for 53 days successively then the testis and epididymis were taken for analysis.
Result: Administration of Eurycoma longifolia and Pimpinella a/pina increased the number and motility of sperms as well as the spermatogenesis. However, there was no difference between the effect of Eurycoma long/folia and Pimpinel!a alpina.
Conclusion: Extract of Eurycoma longifolia and Pimpinell a alpina can improve spermatogenesis.

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Series Title

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Call Number

Media Medika Indonesiana;44(1):210:20-26

Publisher

Semarang : FK Universitas Diponegoro Semarang., 2010

Collation

6p.

Language

ISBN/ISSN

0126-1762

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Edition

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Subject(s)

plants, medicinal
infertility
SPARATOGENESIS

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