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Hipotiroidisme pada Wanita Usia Subur (WUS) di daerah Pertanian:Penelitian di Kecamatan Kersana Kabupaten Brebes

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Hypothyroidism among women 0/ childbearing age (WCA) in the agricultural area: A study in Kersana sub-district Brebes regency Background: Hypothyroidism can cause infertility, spontaneous abortion. fetal growth-development disorders, Placental abruption and prematurity. Exposure to pesticides, both of organochlorines and organophosphate, can cause hypothyroidism. The aim 0/ the study was to examine the prevalence of hypothyroidism in WCA in agricultural areas.
Methods: A cross-sectional study was conducted in two hundred and eight women of WCA who were randomly selected from four Villages and TSH levels were examined. The TSH cut-off point for the diagnosis of hypothyroidism was >4.5 plUlmL. In a sub¬sample,[T4 levels, UEI and thiocyanate in urine, were also examined.
Result: The mean level of TSH was 3.66 (±5.330) utll/ml.. the lowest value was 0.05, and the highest was 60/-dUlmL; the median was 2.38 pIU/mL; the mean FT 4 (n=89) was J6.207±3.0438 pmollL: UEI median value (n=41) was 288.0 mcglL: while the mean of urinary thiocyanate levels (n=4/) was 1.468±1.25 mcglmL. There were 47 WCA (22,6%) with hypothyroidism, 46 of which (97.9%) are sub-clinical hypothyroidism.
Conclusion: The prevalence o/hypothyroidism in WCA was 22.6% and a/most all women had sub-clinical hypothyroidism. Pesticide exposure is suspected as a risk factor for hypothyroidism in this population.

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Series Title

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Call Number

Media Medika Indonesiana;44(1)2010:13-19

Publisher

Semarang : FK Universitas Diponegoro Semarang., 2010

Collation

6p.

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ISBN/ISSN

0126-1762

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Subject(s)

women
hypothyroidism

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