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Predictive Factors for Pregency in IVF: An Analysis of 348 Cycles

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Objective: To determine predictive factors for pregnancy after IVF.
Method: The subject of this study were three hundred and forty eight IVF cycles in 266 couples who underwent controlled ovarian hyperstimulation in IVF cycles between January 2005 and March 2010. Categorical variables were compared using Chi Square test and continuous variables were analyzed using Independent Hest, p < 0.05 was considered statistically significant. Multivariate logistic regression analysis was done to test correlations between clinical variables and the occurrence of pregnancy.
Results: The women's age significantly influenced pregnancy rate since women under 35 years old has the best chance for preg-nancy (56.4%). Endometrial thickness on the day ofhCG adminis-tration also significantly influenced pregnancy in Ivf (p < 0.001) because 64.1 % of pregnancy occurred if endometrial thickness ~ 10.95 mm. Serum FSH on 3rd day of period that can predict ovarian reserve also has significance on pregnancy. On the other hand, 61.5% pregnancy occurred if more than 6 mature oocytes were re¬trieved (p < 0.00 I). Among 92 patients of 348 cycles we found strong correlation between AMH level with number of mature 00- cytes retrieved (p. < 0.001; r 0.659). Logistic regression done re¬vealed the coupl~ with best chance of pregnancy can be described as follows: women with endometrial thickness ~ 10.95 mm, number of mature oocytes > 6 and age under 35 years old.
Conclusion: This study enabled the characterization of many prognostic factors for pregnancy.

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Series Title

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Call Number

Majalah Obstetrics dan Ginekologi Indonesia;34(4)2

Publisher

Jakarta : Jakarta., 2010

Collation

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Language

English

ISBN/ISSN

0303-7924

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Edition

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Subject(s)

pregnancy
IN VITRO

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