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Effect of Administering Enteral Nutrition pre Caesarean Section Towards High Sensitivity C-Reactive Protein Levels
Objective: To determine the effect of enteral nutrition pre cae-sarean section (CS) on high sensitivity C-Reactive Protein (hsCRP) serum levels post CS.
Method: This clinical trial study on elective CS patients with lumbal anesthesia, was done to compare hsCRP levels two hours pre and 48 hours post CS between the treatment group (P) who was given 200 ml enteral nutrition per oral and control group (K) re¬ceived 200 ml sweet tea two hours pre CS. The study was already approved by the Ethical Clearance Research Committee of Faculty of Medicine University of Indonesia.
Results: Twenty seven elective CS patients in Rumah Sakit Umum Daerah (RSUD) Bekasi were selected using certain criteria and divided into two groups using block randomization. Data col-lected included age, gestational age, nutritional status, indication, of CS total blood volume, and duration of CS, as well as energy intake of energy and protein. Laboratory hsCRP serum levels were exa¬mined two hours pre and 48 hours post CS. Statistical analysis were performed using t-test and Mann- Whitney, with 5% level of signifi¬cancy. Twelve subjects in each P and K group, completed the study respectively. The mean of age was 30.08 ± 4.01 years. The nutri¬tional status based on upper mid arm circumference in both groups was normal, while using kartu menuju sehat (KMS) in all of sub¬jects were classified as overweight. The characteristic of the two groups closely matched at base line (p > 0.05). There was increased hsCRP serum at post CS which was higher in the K group and sta¬tistically significant (p = 0.00).
Conclusion: Administration of 200 ml enteral nutrition two hours pre CS is associated with a reduction of 48 hours post CS hsCRP serum level compared with sweet tea.
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