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Risk of Malignancy Index of Ovarian Cancer Patients in Dr. Sardjito Hospital, Yogyakarta
Objective: To analyse retrospectively the score of the risk of malignancy index (RMI) in determining malignancy in the patients with ovarian mass in Dr. Sardjito Hospital Yogyakarta.
Method: Retrospective analysis.
Results: Ninety patients with complete medical record and adnexal mass were enrolled in the study from January 2007 to March 2009. Sl1t)jects consisted of 70 patients (77.78%) diagnosed with malignant ovarian mass and 20 patients with benign mass (22.22%), More than half of the malignant ovarian mass were serous carcinomas and at advanced stages (51.43% and 51.43% sub¬sequently). Univariatc analysis presented significant difference for ultrasound score and serum Ca-125 level in identification of ovarian malignancy, but not with the age or the menopausal status. The per¬fonnance of RMI (~ ZOO for malignancy) had a sensitivity of 70%, a specificity of 75%, a positive predictive value of 90.74%, and negative predictive value of 41.67%. The serum Ca-125 level had a sensitivity of 81.43%, a specificity of 60%, a positive predictive value of 87.69%, and a negative predictive value of 48%. The ultra¬sound score had a sensitivity of 65.71 %, a specificity of 65%, a positive predictive value of 86.79%, and a negative predictive value of35.14%.
Conclusion: Due to the nature of retrospective study, RMI is re¬liable for identification of malignant and benign ovarian mass im-prove the management of ovarian mass including referral system and the decision regarding the approach used during surgery.
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