Anti Mullerian Hormone Serum Level Indicated Ovarian Response Inti Controlled Ovarian Hyperstimulation of IVF Cycles | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

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Anti Mullerian Hormone Serum Level Indicated Ovarian Response Inti Controlled Ovarian Hyperstimulation of IVF Cycles

Budi Wiweko - Personal Name; Andon Hestiantoro - Personal Name; Kanadi Sumapraja - Personal Name; Muharam Natadisastra - Personal Name;

Objective: To evaluate the clinical value of Anti Mullerian Hor-mone serum (AMH) level as one of ovarian response indicator in controlled ovarian hyperstimulation in IVF cycles.
Method: This cohort-prospective study was conducted in Dr.
Cipto Mangunkusumo General Hospital. The subjects of this study were infertile couples who underwent controlled ovarian hyper-stimulation in IVF cycles. The measurement of FSH level, estradiol level, AMH level, and antral follicles count was done in the begin¬ning of IVF cycles. The cycles were divided into two groups, good responder group and poor responder group. Good responder group had three or more mature oocytes, while the poor responder group had two or less mature oocytes. Statistical analysis was donc us¬ing T- Test and Receiver Operator Characteristic area under curve (ROCAUC) to measure the predictive value of AMH, FSH, estradiol, age, and antral follicle count as ovarian response predictors.
Results and Discussion: From 92 IVF cycles, there were 15 poor responder cycles (16.3%) and 77 good responder cycles. AMH serum level was 3.75 ± 2.77 ug/ml in good responder cycles and 1.04 ± 1.39 ug/ml in po~r responder cycles (p < 0.000 I). AMH se¬rum level was more superior than other ovarian response predictors (AUC 0.846) with cut-ofT value of 1.40 ug/ml. AMH serum level 2: 1.40 pg/ml had good predictive value as 'ovarian reserve or ovarian reserve parameter with 81 % sensitivity and 87% specificiry.
Conclusion: AMH serum level was more superior ovarian re¬serve and ovarian response predictor compared to other parameters. [lndones J Obstet Gynecol 2010; 34-3: 114-8]

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Location name is not set Majalah Obsteri dan Ginekologi Indonesia;34(3):114

A0001348

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Series Title: -
Call Number: Majalah Obsteri dan Ginekologi Indonesia;34(3)2010
Publisher: Jakarta : Indonesian Society of Obstetrics and Gynecology., 2010
Collation: 4p.
Language: English
ISBN/ISSN: 0303-7924
Classification: -
Content Type: -
Media Type: -
Carrier Type: -
Edition: -
Subject(s): MULERIAN DUCTS
OVARIAN HYPERSTIMULATION SYNDROM
Specific Detail Info: -
Statement of Responsibility: -

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