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Potensi Probiotik dalam Mekanisme Sistem Imunitas
Probiotik is a living microorganism that impact the host by modulate the immune system, extend the absorpsi process and bowel movement. Furthermore, it prevents intolerancy, has an antimutagenic effect and to control cholesterol level. Bacteria that include to probiotic, produce lactic acid especially from Lactobacillus sp., Bifidobacterium sp., and another species. Gut Associated Lymphoid Tissue (GALT) is an important part of immune system mechanism in the digestive tract, in which the pathogen could invade the host. The slgA has a potency to neutralize the pathogen. A specific strain of Lactobacillus plantarum, IS-10506, indigenous isolate from traditional dadih, fermented milk from west Sumatra, has an immunity potencial, poison tolerancy and adbesion mechanism.Furthermore, it compete against pathogen, poison decontamination and increase the sIgA production. Positif result could perform brush border repair in rat. Lactobacillus sp. has been developed as an oral vaccine.
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