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Pengaruh Pemberian Satu Sesi Latihan Fisik terhadap Kadar Intterleukin-6 dan Von Willebrand Factor pada Tikus Putih (Rattus Norvegicus Galur Wistar) The Efect of One Session Physical Exercise to Interleukin 6 and Von Willebrand Factor Blood Level in While Rat (Rattus Novergicus Strain Wistar)
Heavy physical exercise presumed to cause some changes in endothelial cells through physical and chemical trauma. This research was aimed to assess the influence of one physical exercise session to Interleukin-6 (IL-6) and von Willebrand Factor (vWF) as one 01 parameters lor endothelial cells damage level. This research is a true experimental study with one way lull randomized design. Forty white rats (Rattus novergicus strain wistar) are divided into 4 groups, each contain 10 rats. The lirst group is given one light physical exercise session (group P1), the second groups given one session 01 moderate physical exercise (group P2), the third group is given one session 01 heavy physical exercise (group P3), and the last group is control. After intervention, the IL-6 and vWF blood concentration 01 the rats was measured by ELlSA technique using R&D system's kit. The difference 01 average blood concentration between groups were analyzed by ANOVA test continued by Benlerroni. The result showed that significant difference 01 average IL-6 and vWV concentration between groups. After continuing with Post Hoc analyze, there is Significant difference between control group and the third group lor IL-6 (p= 0.008), meanwhile there is no Significant difference for vWF ( p>0.05). In conclusion, there was significant improvement 01 IL-6 but not with vWF blood level after giving one session 01 heavy physical exercise.
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