Uji Efek Anti Inflamasi Ekstrak Etil Asetat Buah Semu Jambu (Anacardium Occidentale L.) terhadap Edema pada Telapak Kaki Tikus Putih (Rattus Norvegicus)Jantan Galur Wistar yang Diinduksi Kuragenin | Perpustakaan Badan Kebijakan Pembangunan Kesehatan

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Uji Efek Anti Inflamasi Ekstrak Etil Asetat Buah Semu Jambu (Anacardium Occidentale L.) terhadap Edema pada Telapak Kaki Tikus Putih (Rattus Norvegicus)Jantan Galur Wistar yang Diinduksi Kuragenin

EM Sutrisna - Personal Name; Ma\'at, Suprapto - Personal Name; Domas Fitria Widyasari - Personal Name;

Cashew fruit (Anacardium occidentale L.) has been studied/or its ability as anti inflammation.This research aimed to determine the effect of anti inflammation ethyl acetate extract of cashew fruit (Anacardium occidentale L.) on edema in sole foot ofWistar male rats compared with natrium diclofenac. This research was a laboratory experimental using quasi experimental method. Thirty rats (2-3 month) of 1 50-250 gr were used in this study and divided into 6 groups (5 rats each). The rats werefasted and drinks water was given ad libidiumfor 18 hours. Before rats were treated, the sole foot of rats were measured by pletismometer. After 1 hours, they were injected with karagenin 0,5% 0, 5ml sub plantar pedis. The edema volume in solefoot were measured every 30 minute until 300 minute. This result can be seen at AUC (Area Under Curve) expressed as mean ±SEM, theAUCI).JIK) was calculated and analyzed by ANOVA and continued with LSD (Least Significant Difference). This result showed that the total Area Under Curve (A UC.,,J of edema volume was 130,5 ± 2,1805 in negative control (CMC), 65,55 ± 0,67101 in positive control (natrium diclofenac), 115,8 ± 1,53428 in ethyl acetate extract of cashew fruit doses I (EEA I) equivalent to 450mg/kg BW, 75,95 ± 0,89177 in EEAII (equivalent to 900mg/kg BW), 95,7 ± J,J 5715 in EEAIII (equivalent to 1,8g/kg BW), and 103,65 ± 1,58658 inEEA 11 + Na. The statistical analysis showed that the AUC.,oo of EEA L EEA IL EEA II and EEA 11 + Na were significantly (p

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Location name is not set Biomedika; 2(1):31-35

A0001124

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Series Title: -
Call Number: Biomedika; 2(1)2010:31-35
Publisher: Surakarta : FK. Universitas Muhammadiyah Surakarta., 2010
Collation: 4p.
Language
ISBN/ISSN: 2085-8345
Classification: -
Content Type: -
Media Type: -
Carrier Type: -
Edition: -
Subject(s): inflammation
EDEMA
PLANTS, MEDISINAL
Specific Detail Info: -
Statement of Responsibility: -

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