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Ekspresi Protein Ki-67 pada Sediaan Blok Parafin Jaringan Kanker Paru Jenis Karsinoma Bukan Sel Kecil yang Menjalani Pembedahan

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Background: The Ki-67 protein is a biomarker associated with cell proliferation and from some literature it can be valuable negative prognostic factor in non-small cell lung cancer. We investigated the Ki-67 protein expression in resected non-small cell lung cancer to evaluated the impact on clinicopathological characteristics and postoperative prognosis.
Material and Method: Using monoclonal antibody Ki-67, we immunohistochemically examined 43 surgically resected non-small cell lung cancers to determine Ki-67 expression. We analyzed the prognostic significance in comparison with clinicopathological characteristics and survival between positive Ki-67 expression and negative expression. The positive expression were divided according to mean value into high expression if there is > 10% positive cells by counting 500 cells and low ifthere is

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Series Title

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Call Number

Jurnal Respirologi Indonesia;30(4)2010;206-216

Publisher

Jakarta : Perhimpunan Dokter Paru Indonesa., 2010

Collation

10p.

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ISBN/ISSN

0853-7704

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Edition

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Subject(s)

lung neoplasms
PROTEIN KINACES

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