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Combine Proper Exercise and Regular Taking Antihypertensive Medicine Was Better to Lower Diastolic Blood Pressure Among Diastolic Prehy[ertensive and Hypertensive Subjects

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Aim To prove that proper exercise and taking antihypertensive medicine may reduce diastolic blood pressure (DBP) by 2: 5 mmHg.
Method A quasi-experimentation study was done on employees of a government bureau in Jakarta, for 8 weeks from March to August 2008. All prehypertensive and hypertensive subjects were detected through a survey prior to the quasi-experimentation study. A talk was given at the beginning of the quasi-experimentation study, and weekly counseling sessions on exercise, taking medications, and other related topics continued for 8 weeks. Cox regression was used for calculating relative risk.
Results A total 1,016 employees out of 1,300were involved in this blood pressure survey. Of these, 318 subjects had a DBP of 80 mmHg or more. Out of 120 subjects who voluntarily participated, 104 subjects completed the quasi-experimentation study. Compared to those who did not exercise properly and did not take antihypertensive medicines, subjects who did exercise properly and took medicines regularly had a lower diastolic blood pressure DBP 2: 5 mmHg by more than 12- fold [adjusted relative risk (RRa) = 12.32; 95% confidence interval (Cl) = 0,65-234,54; P = 0.095. However subjects who exercised properly or took antyhypertensive medicines irregularly were found to lower their OBP 2: 5 mmHg by almost 11 fold [adjusted relative risk (RRa) ~ 10.94; 95% confidence interval (Cl) ~ 2.04-58.74]; P> 0.005. Subjects with DBP~ 90- 99mmHg had a decrease ofDBP ": 5 mmHg 4.8 fold (RRa ~ 4.75; 95% Cl ~ 1.19-18.65) compared to those with DBP ~ 80-89mmHg. Compared to the normal subjects, the obese, resting pulse rate bradycardia, and high average pulse pressure subjects had less probability of lowering DBP2: 5mmHg, by 87%, 90%, and 65%, respectively.
Conclusion Combine proper exercise and taking antihypertensive medicine was reduce DBP by 2:5 mmHg among DBP (pre-) hypertensive subjects. The obese, bradycardia, or high pulse pressure subjects failed to lowering their DBP 2:5 mmHg by proper exercise and taking antihypertensive medicine. (Med J Lndones 2009; 19: 191-8)

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Detail Information

Series Title

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Call Number

Medical Jourrnal of Indonesia;19(3)2010:191-198

Publisher

Jakarta : Faculty of Medicine Unversity of Indonesia., 2010

Collation

7p.

Language

English

ISBN/ISSN

0853-1773

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Edition

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Subject(s)

nuclear medicine
hypertension
EXERCICE
HYPOTENSION

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