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Atherosclerosis as the cause of Coronary Heart Disease : A Theoretical Concept Based on Molecular Pathology (Proses Aterosklerosis sebagai Penyebab Penyakit Jantung Koroner: Ditinjau dari Konsep Patologi Molekular sebagai Landasan Teori)
Several theories on the pathogenesis of atherosclerosis may be integrated into a single multifactorial one. According to this theory, the most probable sequence of events involved in early atherosclerosis is a vascular dysfunction or injury, monocyte and macrofage recruitment, lipid deposition, synthesis of extracellular matrix. The interaction of all these factors will create the characteristic formation of the atherosclerotic plaque.
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