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Perbedaan Gambaran Resistensi Insulin Berdasarkan Indeks Home antara Wanita Usia Lanjut Normal dan dengan Toleransi Glukosa Terganggu

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Background: Aging has important role in metabolic impairment. Impaired Glucose Tolerance (IGT) is one of any deterioration of physiological function. Recent study reported that 16% of men elderly with IGT and this condition related with insulin resistance. We have no recent data about IGT in women elderly and is there any correlation with insulin resistance.
Objective: Aim of the study to determine Insulin Resistance Profile Based on HOMA Index Between Normal Elderly Women and With Impaired Glucose Tolerance .
Subject and Methods : Experimental Quasie, OGTT in women elderly population without history of diabetes mel/itus. We measured Fasting Blood Glucose (FBG), fasting insulin (FI), and 2 hours Blood Glucose (2hBG) level after OGTT. Statistical Analysis with non parametric test to determine difference of proportion, Pearson correlation to determine correlation between HOMA index and BGL. T-test to compare mean of continous data. Significantly level 0,05 Confidence Interval 95%
Results: Thirty subjects followed this study. Mean of FBG, FI, 2hBG, and HOMA index were 91,4:!:.6,3 mg/dl; 6,64:!:. 4,0 uIU/L; 121,5:!:.34,1 mg/dl; 1,52 .! 1,0. Weak correlation between HOMA index and FBG, 2hBG level. Twenty subjects non IGT and 1(5%) of them with insulin resistance. Ten subjects with IGT and 2 of them with insulin resistance. No significantly different in subjects proportion with insulin resistance between non IGT and IGT group. Weak correlation between HO MA index and FGB in IGT group. Compare mean of HOMA index betweennon IGT and IGT group was 1,35:!:.0,7 vs. 1,89:!:.1,4 (p>0,05; IK 95%).
Conclusion: No significantly different mean of FBG, Fasting Insulin and HAMA index between non IGT group and IGTgroup

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Series Title

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Call Number

Jurnal Kedokteran dan Kesehatan Indonesia:2(7)2010

Publisher

Yogyakarta : FK. Universitas Islam Indonesia., 2010

Collation

6p.

Language

ISBN/ISSN

2085-4145

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Edition

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Subject(s)

AGED
INSULIN RESISTANCE
GLUKOSE

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