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Pengukuran Kadar Aseton Udara Nafas sebagai Indikator Peningkatan Katogenesis pada Penderita Diabetes Melitus Tidak Terkontrol

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Impaired of carbohydrate metabolism is characteristic of Diabetes Melfitus (DM) subjects that cause dysregulation of glucose uptake by target cell. Ketogenesis is compensation of this condition. The basic of this process is fatly acid oxydation. Increasing of fatly acid oxydation formed ketone bodies that we called acetone and can detected by air breathing. Aim of study to determine corelation between acetone level in air breath test as indicator of fatty acid oxydation and fasting blood glucose level in uncontrolled DM subjects. Cross-sectionel; uncontrolled DM subjects and healthy person as control group. We measured fasting blood glucose (FaG) level and samples of air breath and analyse with spectroscopy fotoacustic laser. Corelation betwen level of acetone and FaG analyse with Pearson corelation. Compare means of acetone level between DM subject and control group analyse with non parametric mann-whitney U test. P value 0,05, Cl 95%. Ten uncontrolled OM subjects and 10 healthy persons as control grou~ was followed this study. Mean of age and body mass index are 48,71: 5,6 vs. 49,21: 4,4 years (p>0,05 IK 95%) and aMI 22,4 1: 2,1 vs. 22,91: 3,8 kglm2 (p>0,05 IK 95%). Level of acetone between OM subjects and control group 2601: 41,1 vs 1771: 18,4 ppm (p

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Series Title

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Call Number

Jurnal Kedokteran dan Kesehatan Indonesia:2(6)2010

Publisher

Yogyakarta : FK. Universitas Islam Indonesia., 2010

Collation

3p,

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ISBN/ISSN

2085-4145

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Edition

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Subject(s)

diabetes mellitus
ACETON

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