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Serum Gastrin Level and Pepsinogen I/II Ratio as Biomarker of Helicocater Pylosri Chronic Gastritis

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To find out biomarker as diagnostic tool of H. Pylori chronic gastritiswho fulfilled the inclusion and exclusion criteria. The diagnosis of H. Pylori chronic gastritis was based on histopathological examination and PCR with ure C primer of the gastric biopsy specimen. In addition, we also performed the examination of serum gastrin, pepsinogen (PG) I and PG (Pepsinogen) II level. By using analysis of receiver operating characteristic (ROC), an optimal cut off point of serum gastrin, PGI and PGII level as well as PGI/PGII ratio was determined. Analysis of bivariate logistic regression was used to determine the involved independent variables and possibilities as biomarkers. Significance level was determined by p value 5.89 pmol/L and PGI/PGII ratio≤13.6 can be utilized as biomarkers of H. Pylori chronic gastritis.

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Detail Information

Series Title

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Call Number

Acta Medica Indonesiana:42(3)2010:142-146

Publisher

Jakarta : Indonesia Society of Internal Medicine., 2010

Collation

4p.

Language

English

ISBN/ISSN

0125-9326

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

gastritis
SERUM ANMYLOID a PROTEIN
HELYCOBACTER PYLORI
PESTINOGEN A.

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