Text
Pengaruh Penambahan Vitamin C pada Suplementasi Besi Folat dalam Meningkatkan Kadar Hemoglobin pada PasienPasca Seksio Sesarea di RSU PKUMuhammadiyah Klaten
Sectio-caesarian (SC) proportion was high at Indonesian hospital such as RS CiptoMangunkusumo Jakarta (35.7%) and RSU PKU Muhammadiyah Klaten (33.8%). Massive blood loss due to SC may cause women at risk for iron-deficiency anemia after birth delivery. This study aimed to determine if adding vitamin C to Fe folate supplementation further increase hemoglobin level. Adouble-blinded randomized controllec trial was conducted at KPU Muhammadiyah Klaten, Central Java. A sample of 32 anemic women after SC birth delivery were allocated to either experimental group or control group. All study subjects were given capsules containing 200 mg ferrous sulphate and 0.25 mg folic. In addition, the experimental subjects received 100 mg vitamin C. These capsules were taken once daily for 60 days. Hemoglobin level was measured by Cynmethemoglobin. Food intake during experiment was recorded by hour food recall. To control for confounding variables after randomization, the incremental effect of adding vitamin C to Fe Folate on hemoglobuin was analyzed by multiple linear regresion model on Stata intercooled 7. Adding vitamin C to Fe folate increased hemoglobin level as much as 7.9 g/l higher than Fe folate alone, and it was statistically significant (b=7.9; p=0.013; CI95% a.9to 14.1), after controlling for age and food intake such as Fe, folic acid, vitamin C, protein, and energy, during experimentation. Adding vitamin C to Fe folate significantly increases hemoglobin level in anemic women after sectio-caesarian birth delivery. Hospitals are recommended to provide Fe Folate+ vitamin C supplementation for anemic women after sectio-caesarian birth delivery to increase hemoglobin level.
Tidak tersedia versi lain