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Allergic Asthma in Children Inherited Transmitted or Both? (The Transmission of Periodontopathic Bacteria Concept)
In theory allergic diseases including asthma was the exposure to a transmissible agent and do not depend on early infection which is said to make children more allergy-resistant. This seems, to be a direct contradiction to the hygiene hypothesis, since epidemiologic exidence can be cited in this theory’s support. The fact that nearly all children with asthma are allergic, but only a small proportion of allergic children have asthma at least raises the possibility that some additional factor is involved. That this additional factor might be a transmissible agent is also suggested by the similarity between the gross epidemiologic patterns of children with ppliomylitis in the 1950s and children with asthma currently. The purposed of this study was to reveal the possible relationship between the transmissions of allergic asthma and periodontopathic. Recent researches showed that periodontopathic bacteria are transmissible from mother and caregivers to infants. In addition, a collaboration research that was conducsed by dental practitioners and pediatricians resealed that Gram negative bacteria were significantly predominant (p=0.001) in uncontrolled allergic asthma children compared to well-controlled ones. Nevertheless, how these two phenomenon related was still uncertan Literatures showed that periodontopathic bacteria modulates host immune respons e and sametimes caused disadvantageas effect to allergic asthma. According to the ability of periodonpathic bacteria and its components to stimulate immunocompetent cells it is possible that they are able to modify host immune response which tens to increase allergic asthma symptoms.
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