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Immunogobulin-G Level on Aggressive Periodontitis Patients Treated with Clindamycin

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Aggressive periodontitis might occur asa a result of complex interplay between bacterial and host defence, therefore, the host susceptibility plays important role. Antinicrobial agents that could enhance host defence are required. Clindamicin in might influence hostdefence. The purpose of this study was to determine the influence of clindamycin on level of Immunoglubulin G (IgG patients with aggressive perdontitis, and its mechantism. This study used the pre-test control group design Eighteen aggressive periodontitis patients were divided into 2 geroups at random Group 1 (treatment): 9 aggresive periodontitis patients were given with clindonycin of 1 50mg orally, 4 times a day, for 7 days. Group 2 (control): 9 aggresive periodontitis patients were given with tetracycline of 250mg orally, 4 times a day for 12 days, and then metronidazole of 200mg orally, 3 times a day for 10 days. Blood sample was colected from vena cabiti mediana. Level of IgG was measured at base line and day 28. Data were analyzed statistically by using t-test (a=0.05). Examination for IgG level showed there was significant difference between pre-test and post-test (p0.05). This study showes that clinadamycin can be used as drug of choince for the treatment of aggresive periodontitis since can improve the immunity status of aggresive periodontitis patients.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Dental Journal: 42(3):118-122

Penerbit

Surabaya : FKG Universitas Airlangga., 2009

Deskripsi Fisik

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Bahasa

English

ISBN/ISSN

1978-3728

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

dental care
CLINDAMYCIN

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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