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Chronic Gingivitis and aphthous Stomatitis Relationship HYpothesis A Neuroimmunobiological Approach.
Traumatic injuries to the oral mucosa in fised arthodontic patients are common, especially in the first week of bracket placement, and accasionally lead to the delevelopment of aphthhous stomatitis or ulcers. Nevertheles, these lesions are of self limiting. The objective of this ttudy is to reveal the concentration between chronic gingitivis and aphthous stomatitis which is still unclear. A patient with a persistent lesion for than six months six month. RAS was treated with scaling procedure, the gingival inflammation was healed. However, in this case report, dispite the appro priate management procedurse had been done, the worsen and became more painful. Moreover, the symptoms did not heal for more than two weeks. Actually, they had been undergone orthodentic treatment more than six months and rorely suffered from aphthous stomatitis. Coincidentally, at that time rhey also suuffered from chrontic gingivitis. It was interesting that after procedures, the ulcer subsides in two days. Recently, the neuroimmunobiological researhes which involved neurotransmiters and cytokines on cell nerve signaling, and heat shock proteins in gingivitis and stomatitis are in progress, they were done separately, this do not esplain the interrelationship. This propased new concept which based on an intergrated neurimmunobiological approach could explan the benefit of periodontol treatment, especially scaling procedures, for avoiding prolonged painful episodes and unnecessary medication in aphthous stomatitis. However, for widely acceptance of the chronic gingivitis and apthous stomatitis relationship, further clinical and laboratory study should be done. Regarling to the relationsive to the relatively fast healing after scaling procedures in this case report; it was concluded that the connection between chronic gingivitis and aphthous stomatitis is possible.
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