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Impact of Iron Therapy on Mentzer Index and Red Cell Distribution Width Index in Primary School Children With Iron Deficiency Anemia
Iron deficiency anemia (IDA) remains a common nutritional problem, especially in school-age children. Due to the many examination that are needed to be performed and the invasive gold standard procedure, an easy and simple alternative examination to diagnose IDA is needed. To determine the impact of iron therapy on Mentzer and red cell distribution with (RDW) indexes of children with IDA. A randomized open clinical trial was conducted in primary school aged children in North Aek Nabara, Between November 2006 and November 2007. Ida was determined based on WHO criteria. Subjects with severe anemia were excluded. Subjects were randomly assigned to groups that recei ved either iron therapy or a placebo. Three-hundred subjects from aged 9 to 12 years old were recruited and 104 subjects completed the study. The mean RDW index of the iron and placebo groups after there months observation were 234.96 (SD 39.25) and 235.17 (SD 31.77), Respectively. The mean Mentzer index mean for the iron therapy and placeo groups after three months observation were 16.08 (SD 1.98) and 16.20 (SD 2.27), respectively. After therapy there are no significant differences in either the Mencer or RDW indexs between the therapy and placebo groups.
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