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Sensitivitas Sp. Penyebab Demam Tifoid terhadap Beberapa Antibiotik di Rumah Sakit Immanuel Bandung

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Typhoid fever is an enteric fever caused by Salmonella sp. Especially Salmonella typhi and Salmonella paratyphi. Vraious antibiotics used for therapy beside chloramphenicol as drug of choice. Non rational use of antibiotics may result increasing of resistence in bacteria. The aim of the research is to know the sensitivity of Salmonela typhi andSalmonella partyphi to some antibiotics. The purpose is to gather information about antibiotics which are stilleffective for typhoid fever and enteric therapy. Salmonella typhi and Salmonella paratyphi atrain from positive cultures diagnose typhoid fever patients at immanuel Hospital Bandung 2004-2007. The method of resistance is Kirby Bauer’s disk diffusion assay with NCCLS standard. The disk antibiotics used are amoxicillin, amoxicillin –clavulanic acid, chloramphenicol, ciproffoxacin, ceftriaxone, trimethoprim, and trimethoprim-sulfamethozole. The result showed penicillin group, amoxicillin and amoxicillin-clavulanic acid had 96.3-99.68% sensitive against Salmonella sp. Sensitivity of chloramphenicol as drug of choice of typhoid fever still 99.05%. Since the senitivity less than 100%, it means there was about 8% resistance. Thats why eventhough this data can be used as empiric therapy, the water suggest to do sensitivity to Samonella sp. That caused typhoid to get rationally dan effective treatment. From the result, it’s conducluded that Salmonella sp. That caused typhoid to get rationally dan effective treatment. From the result, it’s concluded that Salmonella paratyphi are still sensitive to all that antibiotics.

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Series Title

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Call Number

Majalah Kedokteran Bandung:41(3):147-150

Publisher

Bandung : FK Universitas Padjaran., 2009

Collation

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ISBN/ISSN

0126-074X

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Edition

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Subject(s)

SALMONELLA
TYPHOID FEVER
ANTI PACTERAIL AGENTS

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