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Hepatic Enzyme Concentrations as Indicators of Nonaleoholic Fatty Liver Disease

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Nonalcoholic fatty liver diseases (NAFLD) has emerged as world-wide problem because it rums as asymptomatic course, ultimately leading to cirrhosis of the liverand portal hypertension, resulting in death. The prevalence of the diseases accounts for 3-24% of the population in several countries. Generally there are increased concentration of hipatic enzymes as markers of liver damage, such as serum glutamic oxaloacetic transaminase (SGTO), serum glutamic pyruvic transaminase (SGPT) and gamma glutamyl transferase (GGT). The aim of the present study was to determine the concentrations of hepatic enzymes as markers of NAFLD. The study design was cross-sectional, involving 90 subjectts meeting the inclusion and exclusion criteria. The degree of severity NAFLD was determined by ultrasonography and the concentrations of SGOT, SGPT and GGT by automated clinical chemistry analyzer. The results indicated that there were 32 subjects with mild NAFLD (35.6%), 35 subjects with moderate NAFLD (38.9%) and 23 subjectswith severe NAFLD (25.6%). There was a significant difference in degree of NAFLD by gender (p

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Series Title

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Call Number

Universal Medicina:28(3):139-145

Publisher

Grogol Jakarta : Trisakti University., 2009

Collation

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Language

English

ISBN/ISSN

1907-3062

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Edition

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Subject(s)

liver diseases
enzymes
FATHY LIVER

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