Text

Legionella Pneumophila Infection (Infeksi oleh Legionella Pneumophila)

---

Legionella pneumophila infection first came to attention after the outbreak in 1979 which was later known as Legionnaire's disease. There was a similar epidemic with milder symptoms in 1968 that was known as Pontiac disease. The causal microorganism was not found by centers for disease control (CDC) until 1977. Transmission of the disease is commonly by aerosol formed from water environment or microaspiration of contaminated water. L. pneumophilla is an intracellular microorganism, living in the cytoplams of macrophage. Cellular immunity plays an important role in this disease. Legionella can be isolated from products of respiratory tract. It needs L-cystein and iron supplement for its growth. It is an organism characterised by non spore-forming, aerobic, negative Gram rodsa and flagellated. Patients with Legionnaire's disease showed acute sign at the lower respiratory tract, an infection similar to acute bronchopneumoniae. Erythromycin and 5-fluoroquinolon are the antibiotics choice of effective against L. pneumophilla, because its ability to penetrate cell membrane. Prevention and transmission control can be done by decontamination of portable water through chlorination or repeated heating until 55-75 degree C. Continous monitoring of water supplies in hospitals, offices and residental buildings is needed to prevent outbreak of this disease.

---

Availability

Detail Information

Series Title

-

Call Number

Majalah Kedokteran Indonesia,45(4)1995:251-263

Publisher

: ., 1995

Collation

-

Language

ISBN/ISSN

-

Classification

-

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

legionnaires\' diseases

Specific Detail Info

-

Statement of Responsibility

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment