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Multimicronutrient Supplementation and Asymptomatic Urinary Tract Infections in the Elderly
As human life expectancy continues to increase, deleloping countries are reporting higher percentace of elderly in their respective population. The defense mechanisms of the elderly are reduced due to several factors, such as increased susceptibility to infection, specifically urinary tract infection (UTI). A randomised placebo-controlled, double-blin trial was conducted to assess whether multimicronutrient supplementation is effective in reducing UTIs in older people in the community. A total of 261 elderly who leved inMampang Prapatan district, South Jakarta, were randomised to daily multimicrountrient supplementation or control groups. Te primary outcomes were the incidence of asymptomatic URI, the organisms responsible for UTIs nd the results of sensitivity tests on UTI microorganisma. UTI was defined as culture-positive urinarine yielding a single species of organisms in number than 10₄ cfu/mL urine specimen. At base-line 19.5% of the elderly had UTI, numely 23.7% patients in the MMN group and 16.7% in the group, but the difference was not statistically significant(p=0.158) Escherichia coli was the most common microorganism, isolated in 20.7% of the MMN group and 17.5% of the control group. Alter six months of supplementation, UTI in the MMN group decreased by 40.6^ compared with only14.4% in the control group. The numbers of E. Coli also by 64.3% in the MMN group compared 37.8% in the control group. This study has confirmed the beneficial effect of multimicronutrient supplementation on UTI in the elderly.
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