Text
Pengaruh Pemberian Pegagang (Centella Asiatica) pada Kadar Glukosa Darah, Asupan Makanan dan Kadar Ghrelin dalam Plasma Darah Tikus (The Effect of Centella Asiatica Administration on Plasma Blood Glucosa, Plasma Ghrelin on Rat)
Changes in body weight is September by energy belance. Satiety and hunger is the way of body to meintain balance of energy. Hypothalmus receive variety of sigal to make an adjustment and regualte food intake. Ghrelin is the novel hormone from the stomach which is knowing since 1999 have an ability to increase food intake by stimulating vegal and hungercenter in hypothalamus. Herba Centella (Pegangan) is one of the herb which is usetraditionally to increase driving to eat. We hypotesized that the effect of herb centella to increase food intake is by stimulating secretion of ghrelin. Twenty eight rats was divide in 2 groups, 14 rats was gived aquades orally as controls and 14 rats was gived 50 mg extract of Centella asiatica orraly. The administration was giving at about 11.00 am for 2 weeks. In the group which is treat with extract of Centella show the significance increase of plasma blood glucose but decrease of plasma ghrelin, and no differences infood intake before and after treatment.
No other version available