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Assay Method Validation of Triamcinolone Acetanids (TA) to support the Investigation of TA-Ioaded Nenoparticies

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The aim or this study was to develop the valid analytical method which used for the assay of triamcinolone acetonids (TA) in the investigation of TA-loaded nenoparticle formulations: High Parformance Liquid Chromatography (HPLC) method was aplied in this study by using an Econosil calumn, C18 10um, 250 x 4.6 mm (Alltech Asociates Inc, PA, USA) as the stationary phase. The mobile phase consisted of a compostion of acetonitrile (ACN) and 20 mM phosphate buffer solution (pH 4.2) in the proportion of 20:50 v/v. The HPLC assay of TA was valldated for selectivity, linearity, precsion, recovery (accuracy), sensitivity and stability of TA during the assay. Results whowed that the concentration of TA in the samples can be determined against the standard in the concentration range of celibration curve. The system praction and level of recovery were consisdered to be acceptable, and the method was selective and sensitive.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Majalah Farmasi Indonesia:20(4):178-184

Penerbit

Yogyakarta : Fakultas Farmasi UGM., 2009

Deskripsi Fisik

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Bahasa

English

ISBN/ISSN

0126-1037

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

TRIACINOLONE ACETONIDE

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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