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Correlation of Interleukin-6 and Monocyte Count to Troponin I in AcuteCoronary

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Background: Acute coronary syndrome (ACS) becomes an important diseases, because of its increased prevalence and mortality rates. Makers of systemic inflammation, including interleukin-6 and monocyte count, have been shown to predict future cardiovascular events. However, the association between these inflammatory markers with cardiac injury is still a controversy. Objective: To evaluate the relationship between IL-6 and monocyte count as inflammation markers and troponin I as cardiac injury. Methods: This was a cross-sectional study. Subjects were patients suspected of ACS admitted to the amerency department of Sardjito Hospital Yogyakarta. Diagnoses were performed based on WHO criteria. Troponin 1 and interleukin-6 levels were measured from sera using sandwich ELISA method (Roche). Monocyte sounts were determined by outomatic hematology analyzer (Sysmex). Kruskal-Wallis test and Sperman’s correlation test were used to assess the difference and correlation between parameters. Results: Sixty one (1) subjects were included in the study. Age of the subjects were 51-60 years,and diagnosed as st elevation myocardial infarct (STEMI). Significant differences of IL-6 and troponin I levels were determined among unstable angina pectoris (UAP), non-ST elevantion myocardial infarct (NSTEMI), and SI elevantion myocardial infarct (STEMI). There was a moderate correlation (r=0.54; p=0.001) rnrn

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Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

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No. Panggil

Berkala Ilmu Kedokteran, 40(4): 189-192

Penerbit

Surabaya : Fk. Universitas Gajah Mada., 2008

Deskripsi Fisik

2p.

Bahasa

English

ISBN/ISSN

0126-1312

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

MONOCYTES
TROPONIN
INTERLEUKIN-6

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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