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Bacterial Vaginosis (Vaginosis Bakterialis)

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Gardnerella vaginalis is associated with bacterial vaginosis (formerly called 'nonspecific vaginalis'). Bacterial vaginosis is a defined syndrome with an excessive, malododous vaginal discharge accompanied with a significant increase in the number of G. vaginalis and various obligate anaerobes, mainly Bacteroides spp and Peptostreptococcus spp, and a decrease in the number of vaginal lactobacilli. Diagnosis of bacterial vaginosis can be made by the presence of excessive vaginal discharge, clue cells (vaginal epithelial cells covered by small gram-negative rods), and a fishy, amine-like odor in the KOH test. Although G. vaginalis is found consistently and in high numbers in women with bacterial vaginosis, the organism can also be isolated from healthy women. The pathogenesis of bacterial vaginosis is still unclear; it is thought that some unidentified factors leading to conditions which disrupt the interaction between G. vaginalis and certain anaerobes, resulting in an increase in the number of G. vaginalis.

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Majalah Ilmiah Fakultas Kedokteran Universitas Tri

Publisher

: ., 1995

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Subject(s)

vaginosis, bacterial

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