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One Year Experience using Quinacrine Pellets for Non-Surgical Female Sterilization

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Objective : To evaluate the safety and acceptability of two transcervival application of 250 mg of quinacrine and 55.5 mg ibuproven pellets as non-surgical female sterilization. Design/data identification : A descriptive study was done by recruiting women seeking sterilization for family planning reason. Each women received a 250 mg dose of quinacrine hydrocloride in the form of seven cylindrical pellets. The pellets was inserted twice with the period of two months during the proliferative phase of menstrual cycle. Follow-up was conducted in 6, 12, 24 and 48 months after the last administration. Data were collected using standarized forms developed by the International Federation for Family Health (IFFH). Setting : Family planning clinic, Department of Obstetrics and Gynecology Wonosobo Regency Hospital, Central Java Province, Indonesia. Subject, patients, participants : Two hundred women were studied during the period of from August 1992 to October 1993. All of them fulfilled the inclusion and exclusion criteria. Main outcome measures : complications, complains, pregnancy rate and continuation rate. Results : Mean age and number of live births of women was 33.2 plus/minus 9.75 (SD) and 3.5 plus/minus 0.50 (SD). The main side effects after the first insertion were lower abdominal pain in 116 cases (60.1 percent), there were two cases who experienced severe lower abdominal pain and required antibiotic and analgesic treatment. Other complications reported were chilling (13.5 percent) and leucorrhea (7.8 percent) which subsided without any specific treatment. The cummulative continuation rates per 100 women at 12 months after the last quinacrine pellet insertions was 0.97 plus/minus 0.01 (SE). The pregnancy rate was 0.01. Conclusions : The result of the study indicated that the use of quinacrine pellets diserves to be further developed as a promising, safe and effective method of non-surgical female sterilization, considering the ease of the method.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Majalah Obstetri dan Ginekologi Indonesia,20(1):39

Penerbit

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Deskripsi Fisik

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Bahasa

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

quinacrine
sterilization

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

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