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Antitumor activity of Eubacterium Lentum (TYH - 11) on Various Tumor Cell Lines

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The proliferation of Meth-A and AH60C fibrosarcoma inoculated intraperitoneally was suppressed in all mice given Eubacterium lentum (TYH-11) intraperitoneally. The proliferation of MH 134 hepatoma and L1210 lymphoid leukemia was also suppressed in some of the mice receiving this strain. Among forms of solid tumors, this bacterial strain cured some mice with MH134 hepatoma. The survival times of mice inoculated with B16 melanoma were prolonged by injection of Eubacterium lentum. The antitumor activity induced by pre-administration of this strain against MH134 hepatoma, L1210 lymphoid leukemia and P388 leukemia cells was superior to that produced by post-administration. This strain, however, had no antitumor activity against EL4 lymphoma and Lewis lung carcinoma.

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Medical Journal of Indonesia,5(3)1996:135-141

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: ., 1996

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eubacterium

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