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The Efficacy and Safety of Loratadine-Pseudoephedrine Versus Triprolidine in Allergic Rhinitis Patients (Efikasi dan Keamanan Loratadin-Pseudoefedrin Versus Triprolidin-Pseudoefedri pada Penderita Rinitis Alergik)

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Allergic rhinitis is a common diseases encountered by ENT specialist as well as general practitioner. Allergic rhinitis can be treated by allergen avoidance, immunotherapy, food neutralizing treatment, surgical intervention or symptomatic treatment. At present there are several combination of HI-antagonist, which do not easily penetrate the blood brain barrier such as laratadine pseudoephedrine, and this have less side effects. This study was conducted at the ENT Allergy Clinic, Hasan Sadikin Hospital Bandung for period of 6 months, (February 1995 to July 1995). One group of patients was given loratadine-pseudoephedrine and the other group triprolidine-pseudoephedrine. After fourteen days of treatment, the results was evaluated by using Mann-Whitney statistical method. It was found that there was no significant difference in the amount of nasal discharge, severity of nasal obstruction, or frequency of sneezing; except for it chy sensation of the nose, ear and/or palate which showed a significant difference (p less than 0.05). Objective assesment of laratadine-pseudoephedrine had less sedative side effects (p more than 0.001) compared with triprodine-pseudoephedrine.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Majalah Kedokteran Indonesia,46(7)1996:357-364

Penerbit

: ., 1996

Deskripsi Fisik

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Bahasa

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

rhinitis

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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