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Antimicrobial Selected for Respiratory Tract Infections (Pilihan Antimikroba untuk Infeksi Saluran Nafas)

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Respiratory tract infections are commonly found health problems in daily practice. Various microorganisms may be the causative pathogens and many antimicrobial agents are claimed to be effective to overcome the problem. Rational choice of antimicrobiolal agents should be based on empirical experience what is the most likely pathogen(s) for a particular respiratory tract infection, followed by choosing the most appropriate drug to eradicate the particular pathogen. Other influencing factors in this respect are age, source and severity of the infection, function of the excretory organs, etc. In choosing antimicrobial drug(s) for respiratory tract infections, preference should be given to the drug of choice. Alternative drug is used if the drug of choice cannot be given for a particular reason. Antimicrobial agents commonly used as drugs of choice for upper respiratory infections are the penicillins, macrolides, tetracyclines, and chloramphenicol. The cephalosporins are rarely considered as first choice for upper respiratory tract infections. For lower respiratory tract infections, however, the second and the third generations of cephalosporins are frequently the most preferred drugs. The presently marketed fluoroquinolones are generally not the drug of choice for respiratory tract infections due to their marginal efficacy against streptococci. These agents are used mainly in the situations where gram-negative.

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Majalah Farmakologi dan Terapi Indonesia,12(1)1996

Publisher

: ., 1996

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Subject(s)

respiratory tract infections

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