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Leukocyte Esterase Dipstick to Diagnose of Mucopurulent Cervicitis : Study among Female Sexual Workers (Dipstik Leukosit Esterase untuk Diagnosis Servisitis Mukopurulenta : Kajian pada Wanita Pekerja Seks)
Mucopurulent Cervicitis (MPC) is an endocervical inflammation that causes a variety of complications, including infertility. The diagnosis of MPC is usually confirmed by counting the number of leucocytes using a Gram stain of an endocervical swab. The method requires trained personnel, microscopic equipment and time to read the result, so the detection of MPC in primary health care setting is often difficult. The Leucocyte Esterase Dipstick (LED) is an easy and rapid method designed for setecting leucocytes, although its role for diagnosing MPC needs to be clarified. In order to test whether LED could be used as gram strain substitute for diagnosing MPC needs to be clarified. In order to test whether LED could be used as Gram strain substitute for diagnosing MPC, a diagnostic study was conducted among 145 female sex workers seeking reproductive health care from Griya Lentera STD clinic, managed by the Indonesia Planned Parenthood Association in Yogyakarta. Endocervical swabs were taken from each subject for gram staining, a gonorhoeae culture and LED examination. The result showed that compared to gram staining, the LED had 96.7 percent sensitivity, 64.81 percent specificity, a Positive Predictive Value (PPV) of 82.2 percent and a Negative Predictive Value (NPV) of 92.1 percent. Compared to the gonorrhoeae culture, the LED had 100 percent sensitivity, 32.2 percent specificity, a PPV of 25.23 percent and a NPV of 100 percent This study concluded that among women at high risk for STD infection the LED could be used as a gram stain replacement in the diagnose of MPC and as an initial method to eliminate MPC caused by gonorrhoeae.
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