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Analisis Kuantitatif Artemisinin dari Ekstrak Metanol Tanaman Artemisia Annual L. Menggunakan Densitometer

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Artemisinin is the besi antimalaria for chloroquine resistant P. falciparum recommended by WHO in a combination therapy. Artemisnin is isolated from Artemisia annua L (family: Asteraceace) that can grow as is should be I Indonesia and has cultivated by BPTO Tawangmangu in order to self-material antimalaria. One of the important analysis is method for measuring artemisinin concentration in extract. The method should be more rapid, accurate, and suitable with the instruments available. Measuring analysis are used to determine cultivated result and to analyze cost benefit raw material malaria medicine. The method will also be validated for accuracy, precision, selectivity, sensitivity and linearity. It is found that maximum wave length of artemisinin is 366 nm with TL-densitometry validated method, shown a good linearity, a coefficient of correlation of 0.999976, a detection limit of 0.028 mg/mL, and a quantitative limit of 0.094 mg/mL. Artemisinin concentration obtained methanol extract is 0.221% with a concentration of 101,08%.

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Detail Information

Series Title

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Call Number

Jurnal Kefarmasian Indonesia,1(!): 33-43

Publisher

Jakarta : Puslitang Biomedis dan farmasi Badan Litbang Kes., 2009

Collation

11p.

Language

ISBN/ISSN

2085-675X

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

plants, medicinal
ARTEMISININS
DENSITOMETRY

Specific Detail Info

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Statement of Responsibility

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