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Karakterisasi dan Toksistas Akut pada Minyak Buah Merah (Pandanus conoideus Lam)

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Buah Merah (Pandanus conoideus Lam), is an endemic plant from Paua and its surrounding Oil of bauah merah know and claimed for cancer, HIV/AIDS, lung tuberculosis, diabetic and decreased blood cholesterol treatment. Since buah merah oil wildly is used in communities, safety test is needed. There were no toxic effects as abnormal behavior or mortality in rats, even using in high dose of, 5 ml/200g body weight or approximately 9.4 times of human dose (axIID=30 ml). Due to this situation, the acute toxicity has been done by biomedical and Pharmaceutical Research and Development Center, at 2006. The result showed that qualitative test based on chemical group compounds, triterpenoid, phenol and steroid have been found clearly. Basically the oil is not toxic for single dose. Since there’s no mortality, the LD50 will be considered as pseudo LD50 that means that doses of 5 ml/200 g body weight of Wistar rat is safe for utilization or the safety dose for human will bein a very large range.

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Series Title

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Call Number

Jurnal Kefarmasian Indonesia,1(!): 18-24

Publisher

Jakarta : Puslitang Biomedis dan farmasi Badan Litbang Kes., 2009

Collation

7p.

Language

ISBN/ISSN

2085-675X

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

plants, medicinal
ACUTE TOXOCOTY TESTS

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