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Deep Vein Thrombosis in Acute Myelogenous Leukemia

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Thrombotic complications in acute leukemia are often underestimated because bleeding complications generally dominate the clinical picture. While there are many thrombogenic factors shared by both solid tumors and leukemia, many additional prothrombotic feactures are present in leukemia. The prothrombotic factors include hyperleukocytosis, increased expression of tissue factor and its activation in leukemic cells, and vascular access cathethers. A 18-year old women came with swelling on her right leg 10 days before hospital admission. Since 2 months before she had weakness, pallor and fever without bleding manifestation. Hematologic examinations showed anemia, leukocytosis with monoblast and thrombocytopenia. Dep veinthrombosis in right femoral and popliteal vein was confirmed using compression ultrasonography. The treatment of such complication is challenging because of the high risk of hemorrhage in this group of patients especially due to their severe thrombocytopenis.

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Detail Information

Series Title

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Call Number

Acta Medica Indonesiana, 41(4): 200-204

Publisher

Jakarta : RS. Cipto Mangunkusumo., 2009

Collation

5p.

Language

English

ISBN/ISSN

0125-9326

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

VENOUS THROMBOSIS
LEUKEMIS, MYELOID

Specific Detail Info

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