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Hypoadiponectinnemia: A Risk Factor For Metabolic Syndrome

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To find out correlation between plasma adiponectin levels, insulin resistance and IDF criteria of Mets Patients levels, insulin resistance and IDF criteria of Mets Patients. A case-control study was conducted on Native Javanese people from June 2006 to Januari 2007 in Outpatients Clinic of Dr. Sardjito Hospital. The case group involved patients aged between 20 to 55 years old. The diagnosis of metabolic syndrome was confirmed according to IDF criteria> Patients without metabolic syndrome with matching age and sex, were taken as control group. There were significant differences between case and control group for BMI (body mass index) (30.2+4.1 vs 26.9+4.7 kgm²), waist circumference (93.5+7.9 vs 84.4+ 11.5 cm), triglyceride (207.4+101.8 vs. 119.3+71.5 mg/dL), HDL cholesterol (48.6+9.4 vs.59.9+11.8 m g/dL, systolic blood pressure (132.8+17.9mmHg vs 120.6+13.5 mmHg) and diastolic blood pressure (83.8+40.8 mg/dL vs. 100.7+29.4 mg/dL), HOMA index (6.7+17.4 vs.20+ 2.0) and adiponectin levels (3.8 +1.4 vs.5.9+2.5), respectively. For metabolic syndrome, hypoadionectinemia showed the OR value of 6.0 (95%CI 1.3 to 25.02), after adjustment for waist circumference, TG.HLD, blood pressure, fasting blood glucose. Hypoadiponectinemia and insulin resistance represent independent risk factors for metabolic syndrome development.

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Detail Information

Series Title

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Call Number

Acta Medica Indonesiana, 41(1): 20-24

Publisher

Jakarta : R.S. Cipto Mangunkusoma., 2009

Collation

4p.

Language

English

ISBN/ISSN

0125-9326

Classification

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Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

METABOLIC SYNDROME
INSULIN RESISTANCE

Specific Detail Info

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