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Hypoadiponectinnemia: A Risk Factor For Metabolic Syndrome

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To find out correlation between plasma adiponectin levels, insulin resistance and IDF criteria of Mets Patients levels, insulin resistance and IDF criteria of Mets Patients. A case-control study was conducted on Native Javanese people from June 2006 to Januari 2007 in Outpatients Clinic of Dr. Sardjito Hospital. The case group involved patients aged between 20 to 55 years old. The diagnosis of metabolic syndrome was confirmed according to IDF criteria> Patients without metabolic syndrome with matching age and sex, were taken as control group. There were significant differences between case and control group for BMI (body mass index) (30.2+4.1 vs 26.9+4.7 kgm²), waist circumference (93.5+7.9 vs 84.4+ 11.5 cm), triglyceride (207.4+101.8 vs. 119.3+71.5 mg/dL), HDL cholesterol (48.6+9.4 vs.59.9+11.8 m g/dL, systolic blood pressure (132.8+17.9mmHg vs 120.6+13.5 mmHg) and diastolic blood pressure (83.8+40.8 mg/dL vs. 100.7+29.4 mg/dL), HOMA index (6.7+17.4 vs.20+ 2.0) and adiponectin levels (3.8 +1.4 vs.5.9+2.5), respectively. For metabolic syndrome, hypoadionectinemia showed the OR value of 6.0 (95%CI 1.3 to 25.02), after adjustment for waist circumference, TG.HLD, blood pressure, fasting blood glucose. Hypoadiponectinemia and insulin resistance represent independent risk factors for metabolic syndrome development.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Acta Medica Indonesiana, 41(1): 20-24

Penerbit

Jakarta : R.S. Cipto Mangunkusoma., 2009

Deskripsi Fisik

4p.

Bahasa

English

ISBN/ISSN

0125-9326

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

METABOLIC SYNDROME
INSULIN RESISTANCE

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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