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Helicobacter pylori and Gastroduodenale Diseases : A Proposal of Treatment in Indonesia (Helicobacter Pylori dan Penyakit Gastroduodenal Usulan Penatalaksanaan di Indonesia)

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Helicobacter pylori is a gram negative bacteria with spiral S, curved shaped that lives only in microaerophilic condition. This bacteria lives between and underneath the mucous of human gastric mucous. A lot of studies in the world showed that H. pylori has a dominan role in peptic ulcer disease and chronic active gastritis. H. pylori strain which has Cag A, 128 kDa surface protein and positive Vac can cause those diseases. H. pylori detection can be made by invasive (by endoscopical examination) and non-invasive examinations. The prevalence of H. pylori in general population in Indonesia is varied between different areas, children 7.2-28 percent and adult 36-54.3 percent. In Indonesia, the prevalence of H. pylori in chronic gastritis 19.04-86.1 percent and in peptic ulcer 71.4-100 percent. H. pylori eradication still meet a lot of problems due to drugs resistency, high cost of treatment and drug side effects.

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Majalah Kedokteran Indonesia,46(4)1996:179-188

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: ., 1996

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helicobacter pylori
peptic ulcer

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