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Sputum Bacterioogy of Acute Bacteria Exacerbations of COPD with Quantitative Sputum Culture: Microbiological and Antimicrobials Resistance Pattern
This study was undertaken to ivestigate microbiological pattern and the related antibiotic resistance of acute bacterial exacerbation of COPD in Persahabatan hospital. The relationship between sputum bacteriology and severity of COPD obstruction was also evaluated. The cross-sectional study, 87 sputum specimens was assesed with Gram’s smears by using Bartlett’s score criteria. A quantitative sputum culture was oerformed, and bacterial growth was considered significant only when the germs was isolated at concentrations >10 pangkat 6 cfu/mL (>10 pangkat 5 cfu/mL for S pneumoniae). Five germs significant quantitative cultures isolated wee the following: S Pyogenes (50%), P aeruginosa (15.4%), S ß-haemolyticus (13.5%), S pneumoniae (11.5%) and K pneumoniae (9.6%). Sensitivity patterns gems to antibiotics: levhown to be most active antibiotics tocover five germs causing exacerbation of COPD. Patients COPD with the greatest degree of obstruction (FEV,
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