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Breastfeeding and Early childhood caries (ECC) severity of children under three years old in DKI Jakarta

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Preeclampsia is a disease in pregnancy and carcterized by hypertension and proteinuria. Preeclampsia and eclampsia are the must causes of maternal and fetal mortality and morbidity in Indonesia. Placental and systemic oxidative stress caused endothelial cell dysfunction and injury. Placental oxidative stress also linked to fetal growth restriction. HSP70 is essential for cellular recovery, survival and maintenance of homeostasis. The purpose the MDA, a marker for oxidative stress and HPS70 production on placental of severe preeclampsia, mild preeclampsia and normotensive pregnant women. Placenta were collected after delivery from normotensive pregnancies (N=10), severe preeclampsia (N=10) and mild preeclampsia (N=10). Placenta was cultured in RPMI and 20% FBS, and supernatant were collected in day 4. MDA was measured using spectrophotometer and absorbance read in 530nm. HSP70 was measured using enzyme-linked immunosorbent assay. The mean MDA concentration did not differ significantly between patients with severe preeclampsia (7.13+5.36 nmol/ml) and mild preeclampsia (4.82+2.47 nmol/ml) when compared with normotensive pregnancies (4.57+2.4 nmol/ml) the mean HSP70 concentration in mild preeclampsia is highest (10.15+12.39 nmol/ml)

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Series Title

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Call Number

Makara (seri Kesehatan): Vol. 12 (2) 2008, 86-91

Publisher

Depok : Kampus Universitas Idonesia., 2008

Collation

6 p

Language

ISBN/ISSN

1693-6728

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Carrier Type

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Edition

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Subject(s)

pre-eclampsia
Placenta
MALONDIALDEHYDE.

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