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Perbandingan Hasil Akhir Pengbatan Antituberkulosis Kombinasi Dosis Tetap (KDT) dengan Kombipak pada Pengobatan Tuberkulosis aru dengan Strategi DOTS di Puskesmas Kecamatan Jatinegaa, Pulogadung dan Matrama Jakarta Timur.

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Combipack, anti-tuberculosis drug which is used in (Indonsa’s National Tuberculosis Programe has been available since 1993. This formulation has high effectviy tuberculosis treatmet, likewise cure rate result still lower. It was influence by patient do not adhere to treatment and many factors. Effective treatment of tuberculosis patient do not adhere to treatment and many factors. Efective treatment of tuberculosis patient with short-course multidrug chemotherapy is the cornerstone of the modern approach to the control the disease. To emphasize this principle, WH and the International Union Againts Tuberculosis and Lung Disease (IUATLD), together with their partners, recommend the use of the fixed-dose combination (FCD) formulation of the essential anti-tuberculosis drugs as one further step to ensure adequate treatment of patients. In 1999 Indonesia had been used FCD in preliminary studies in health centres in the South Sulawesi Province with excellent result for the Combipack and the FDC regiements. In Jatinegara, Martaman and Pulogadung Community Health Centres, East Jakarta, DKI Jakarta Province, never use the FDC. So we study to compare the end result of anti-tuberculosis drugs FDC with Combipack on treatment the pulmonary tuberculosis with DOTS strategy. A Prospective, open randomized negative clinical trial is performed to cmpare the end result of anti-tuberculosis drugs FDC with Combipack on treatment the pulmonary tuberculosis with DOTS strategy. The sampling procedure was consecutive sampling. Samples were patients with new smear-positive pulmonary tuberculosis, informed consent and standard recording and reportng. Patient fufilling the inclusion are randomly allocated to either the Combipack of FDC regmen. For each of the drugs needed in the treatment of tuberculosis, there are a well defined recommended dose per kg body weight. There were 94 patient (47 treated with PDC). During the treatmet, there were 1 patient completed therapy, 1 transfer out, 1 patient failure therapy on the FDC regimens. The Combipack reimens results, conversion rate was 91,5%, success rate was 95,7%, cure rate was 95,7% and the FDC regimens result, conversion rate was 97,%, success rate was 95,7%, cure was 95,7%. Interestingly no significant different results wih the both. The FDC regmens have similar efficacy at finakl treatment of the and result with the Combpack regimens I the management f pulmonary tuberculosis.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Jurnal Respirologi Indonesia, 28(3):45-154

Penerbit

Jakarta : Perhimpunan Dokter Paru Indonesia., 2008

Deskripsi Fisik

10p.

Bahasa

ISBN/ISSN

0853-7704

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

tuberculosis, pulmonary
ANTITUBERCULOSIS AGENTS

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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