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Perbandingan Hasil Akhir Pengobatan OAT Kombinasi Dosis Tetap (KDT) dengan Kombipak pada Pengobatan TB Paru dengan Strategi DOTS

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Although compbipack has high effectivity in tuberculosis treatment but it has lower copliance. The unsccessfull problems might be caued by number of pils taken by patents. Therefore, World Health Organization (WHO) decided to make new preparation which consist of more tan two anttiterculosis agent in one pill which is called fixed dose combination (FDC). The eficacy of 2 antituberculosis agent (FDC and combipack) were compared after 6 months therapy of positife acid fast bacilli (AFB) pulmonary tuberculosis (PTB) patients in directly observed treatment, short course (DOTS) in Lung Clinics Persahabatan Hospital – Department Pulmonology and Respiratory Medicine Medicine, Faculty of Medicine University of ndonesia, with design randomized clinical trial. FDC group consist of 52 patients, 32 male (mean of age 28.56±1.74) is compared to 58 patients,33 male I combipack group (men of age 28.53±10.1). Sputum conversion is 98% in FDC group and combipack 94.7% in the early evaluation, the results almost similar to the end of evaluation 97.3% in FDC group and combipack 97.7%, and both of them are not statistically significant p>0.005). Cure rate in FDC group is 69.2% and combipack 72.4%, and success rate n FDC group is 97.7%, bot of them are not statistically (p>0.005). FDC causing less itchy skin (1.9% in FDC and 6.9% n combipack) an musculoskeletal pain (0% in FDC and 5.2% in combipack) than combipck although is has no satistical significant (p>0.005). FDC has the same efficacy as combipack which can be used to treat PTB in DOTS stategy. Conversion rate, cure rate and success rate are almost the same I bot groups.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

Jurnal Resirologi Indonesia, 28(3): 126-135

Penerbit

Jakarta : Perhimpunan Dokter Paru Indonesia., 208

Deskripsi Fisik

10p,

Bahasa

ISBN/ISSN

0853-704

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

ANTITUBERCULOSIS AGENTS

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

Lampiran Berkas

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