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Hubungan Autlogous serum skin test (ASST) dengan keparahan klinis urtikaria kronik idiopatik di RSUP Dr. Moh. Hoesin Palembang (Severity of Chronic idiopathic in RSUP Dr. Hoesin Palembang)
There were differences in clinical finding among about autologous serum skin test/ASST result in chronic idiopathic urtikaria/CIU. Some research reported there was no significant differences in clinical feature of CIU, whereas other research found significant differences in duration and itch of CIU patients. The prevalence of urticaria in General Hospital Dr. Moh. Hoesin Palembang showed increased tendency but there. The prevalence objectives of this study were to find out the significant correlation between ASST and severity of clinical features of CIU, and compared the difference of clinical features of CIU with and without positive ASST. The study was an observational analytic study, with cross sectional design. Fifty four subjects included in this study after following selection. Ethical approval was obtained from Bioethics and Humanities Units. Faculty of Medicine Sriwijaya University and Dr. Moh. Hoesin Palembang.
The clinical feature with CIU were evaluated. The data of physical examination and the anamnesis about clinical score collected and analyzed using SPSS software and spierman correlation was used to analyze the correlation between clinical severity of CIU and ASST result. Student’s t-test was used to analyze the difference in clinical severity of CIU with and without positive ASST. there was significant correlation between the severity clinical feature CIU and ASST result (p=0,00; R=0,598). Patient with positive ASST results (46,5%) hade more duration of illness (0,00), higher pruritus score (0,00), and angiodema score (0,024). The ICU patients with severity clinical score 0r 27 (cut-of point), 11 times more likely to develop autoimmune urticaria than the patients with cut-off bellow 27 (p 0,00)
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