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The Findings of Sitology, Colposcopy, and Histology Examination of Subclinical Infection of Human Papilloma Virus on Women in High-Risk Group (Temuan Hasil Pemeriksaan Sitologi, Kolposkopi dan Histologi Infeksi Subklinis Virus Papiloma Human pada Serviks Wanita Golongan Risiko Tinggi)

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Objective : Evaluate the findings of sitology, colposcopy and histology examination and incidence rate of subclinical of human papilation virus on the cervix of high-risk women. Data formulation: Descriptive study, data during 3 months (April to May 1995). Subjects: patients, Participants: One hundred one women masseuse at Taman Impian Jaya Ancol who have undergone Pap test, Colposcopy and Biopsy directed at lesion with abnormal colposcopic appearances. Main external size : Age, material status, the age of first sexual intercourse during the marriage, sitologic findings of HPV or NIS infection, normal or abnormal colposcopy findings, and histology findings of HPV or NIS infection. Results: Participants characteristics were: mostly (71.3 percent) 20-35 years of age, 52.5 percent with marital status as widow, and 7.9 percent unmarried, 96 percent had their first sexual intercourse at the age of 20 or younger, and 86 percent have been married at the age of 20 or younger. In all the participants, a colposcopy and Pap test examination was done with the result of abnormal colposcope appearances in the form of white and punctate epithelium in 67 cases (66.4 percent). The results of sitology from Pap test: 7 cases (6.9 percent) showed HPV infection, 8 cases (7.9 percent) HPV + NIS infection 1.3 cases (3 percent) NIS 1.3 cases with no specimen, and 80 cases (79.2 percent) normal. Histology examination of biopsy findings of 67 cases with abnormal colposcopy showed HPV infection in 37 cases (55.2 percent) with one case accompanied by NIS 2 appearances, and one cases with NIS 1, While of the other 29 biopsies (43.3 percent) histology findings were found normal. The correlation between sitology findings with histology of HPV infection was found only in 7 (19 percent) cases. The rate of incidence of HPV infection based on histology findings was 36.6 percent. The relative higher risk for being infected with HPV found in the age group of 21-30 years old (1:2.2), and the overall relative risk was 1:2.7. Conclusion: The rate of HPV subclinical infection in the cervix of high-risk women group was rather high (36.6 percent), and colposcopy examination in conjunction with Pap test is better than the Pap test in detecting cervical HPV infection in high-risk women group.

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Majalah Kedokteran Indonesia,46(2)1996:61-65

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: ., 1996

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colposcopy
papilomaviruses

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